PRP vs Polynucleotides vs Exosomes

Regenerative aesthetics has transformed the way we approach ageing, scarring, and damaged skin. Instead of simply filling, tightening, or resurfacing the skin, regenerative treatments work by activating the body's own repair systems. At Our Skin Clinic, we specialise in advanced regenerative treatments including PRP, polynucleotides (Plinest), and exosomes (Purasomes) — three cutting-edge options that are redefining non-surgical rejuvenation.

This blog explains how each option works, who it's best for, and the scientific evidence behind it.

What Is PRP?

Platelet-Rich Plasma (PRP) uses the healing components in your own sample — platelets, growth factors, and cytokines— to stimulate tissue repair, collagen formation, and cellular turnover.

Research shows PRP:

Improves skin texture, Skin treatments for fine lines, and pigmentation
Enhances wound healing
Stimulates collagen and elastin production

A 2019 systematic review in the Aesthetic Surgery Journal found that PRP improves skin quality by triggering fibroblast proliferation and increasing collagen density in the dermis.

At Our Skin Clinic

We offer:

PRP Vampire Facial (Microneedling + PRP)
PRP Under-Eye Rejuvenation
PRP Face, Neck & Décolletage
PRP Hair Restoration

These treatments are ideal for clients seeking natural rejuvenation with minimal downtime.

What Are Polynucleotides (Plinest)?

Polynucleotides (PNs) are fragments of purified DNA that stimulate cellular repair, hydration, and collagen regeneration. They work by improving the skin's extracellular matrix, boosting fibroblast activity, and reducing inflammation.

Recent evidence supports their effectiveness. A 2023 review in the Journal of Cosmetic Dermatology concluded that PN treatments significantly improve skin elasticity, hydration, and dermal thickness while reducing signs of ageing.

At Our Skin Clinic

We use Plinest, one of the highest-quality, medically regulated PN products available. It is particularly effective for:

Under-eye creping
Early signs of ageing
Loss of elasticity
Overall skin quality improvement

PNs are perfect for clients wanting deep hydration and tissue repair without adding volume.

What Are Exosomes (Purasomes)?

Exosomes are ultra-small signalling molecules naturally released by stem cells. They carry proteins, growth factors, peptides, and genetic material that instruct skin cells to repair, regenerate, and function more youthfully. In aesthetics, they are considered one of the most advanced regenerative tools available.

Recent research highlights their potential:

A 2020 study in Stem Cells International found exosomes promote collagen production and accelerate wound healing.
A 2022 clinical review reported significant improvements in Skin treatments for fine lines, pigmentation, and overall skin texture when exosomes were used with microneedling.

At Our Skin Clinic

We offer Purasomes Exosome Therapy, including:

Exosome Microneedling
Exosomes added to PRP
Exosomes added to PN (super-boost rejuvenation)

These treatments are ideal for clients wanting maximum collagen stimulation and advanced rejuvenation.